Ronald P. van Rij

This study shows that Piwi5 is essential for piRNA production and transposon silencing in Ae. albopictus, with loss of Piwi5 leading to increased transposon activity.

This study shows that Piwi6 in Aedes mosquitoes suppresses LTR retrotransposons in both gonadal and somatic tissues by guiding H3K9me3 histone deposition.

This study identifies prolyl hydroxylation as essential for ZIKV NS1 maturation and secretion, with mutations affecting viral replication and protein stability.

The paper develops a simple piRNA cluster annotation method for non-model insects, validated on mosquito genomes.

The paper investigates how endogenous piRNAs guide slicing of viral RNA in Aedes aegypti mosquitoes, leading to the production of responder and trailer piRNAs.

The paper identifies a piRNA-lncRNA regulatory network in Aedes aegypti mosquitoes that initiates responder and trailer piRNA formation during embryonic development.

The paper presents an improved genome assembly of Aedes albopictus, revealing new biological features and enabling population and developmental studies.

The paper identifies abundant viral integrations in Aedes aegypti and Ae. albopictus genomes that express piRNAs, suggesting a functional link to the piRNA pathway and antiviral defense.