Kohji Moriishi

This paper identifies vorapaxar and aripiprazole as inhibitors of HBV replication through distinct host signaling pathways, showing their potential as host-targeting antivirals.

This study identifies three new hepaciviruses in birds, revealing phylogenetic incongruence and suggesting past cross-species transmission among avian hepaciviruses.

This paper develops a HiBiT-expressing recombinant rat hepacivirus that can infect both in vitro and in vivo, enabling quantitative antiviral screening and pathogenicity studies.

This study identifies claudin-3 as an entry factor for rat hepacivirus, showing host-specificity determined by two amino acids in extracellular loop 1.

This study identifies that HCV infection promotes PA28γ acetylation and heptamerization, enhancing proteasomal degradation of RNF2 and leading to HOX gene expression.