Oral administration of 4-methylumbelliferone reduces glial scar and promotes anatomical plasticity
Kateřina Štěpánková, Milada Chudíčková, Zuzana Šimková, Noelia Martínez-Varea, Šárka Kubinová, Lucia Machová Urdzíková, Pavla Jendelová, Jessica C. F. Kwok
This study evaluates the effect of 4-MU on spinal cord injury in rats, showing reduced HA synthesis and glial scar but insufficient functional recovery.
bioRxiv · Feb 2, 2023 · PreprintNeuroscience