Lucia Machová Urdzíková

This study shows that 4-MU reduces PNNs, improves memory, and decreases neuroinflammation in aged mice.

This study shows that reducing chondroitin-4-sulfation in mice improves cognitive function and mitigates age-related decline without removing CSPGs.

This study shows that long-term PI3Kδ overexpression in adult rat cortex using AAV1 is safe and well-tolerated, with no adverse effects observed over one year.

This study investigates the combined effects of db-cAMP and integrin 9 overexpression on axonal regeneration in spinal cord injury models, finding mixed in vitro and in vivo results.

This study shows that increasing PI3K{delta} activity in adult rat cortical neurons promotes corticospinal tract regeneration and functional recovery after spinal cord injury.

This paper demonstrates that expressing alpha 9 integrin and its activator kindlin-1 in sensory neurons enables axon regeneration through spinal cord injuries in rats, restoring sensory function.

This study evaluates the effect of 4-MU on spinal cord injury in rats, showing reduced HA synthesis and glial scar but insufficient functional recovery.

This study shows that 4-MU removes perineuronal nets and enhances plasticity in the central nervous system, offering a potential oral treatment for spinal cord injury.