Bi-directional allosteric pathway in NMDA receptor activation and modulation
Paula A. Bender, Subhajit Chakraborty, Ryan J. Durham, Vladimír Berka, Elisa Cristina Carrillo, Vasanthi Jayaraman
This study identifies a bidirectional allosteric pathway between the extracellular and transmembrane domains of NMDA receptors, revealing how conformational changes in one domain influence the other.
Nature Communications · Oct 13, 2024Peer-reviewedBiophysics