Kenneth H. Lundstrom

Molecular Genomic Insights into Melanoma Associated Proteins PRAME and BAP1

This study analyzes the molecular features of PRAME and BAP1 proteins in melanoma using bioinformatics methods to identify potential therapeutic targets.

Methuselah Proteins in Longevity: Unraveling Their Impact Through Mathematical Genomics

This study analyzes 18 Methuselah protein variants in fruit flies, identifying evolutionary clades, functional subclasses, and structural features related to aging and longevity.

Unveiling the Genetic Tapestry: Rare Disease Genomics of Spinal Muscular Atrophy and Phenylketonuria Proteins

This study analyzes genetic variations in PAH and SMN1 genes associated with PKU and SMA in Saudi Arabia using quantitative techniques to improve diagnostics and treatments.

SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants

This study analyzes NSP14 mutations in SARS-CoV-2 to understand their role in viral evolution and variant diversification.

The Distal-Proximal Relationships Among the Human Moonlighting Proteins: Evolutionary hotspots and Darwinian checkpoints

This study analyzes human moonlighting proteins using phylogenetic methods to explore their distal-proximal relationships and identify evolutionary hotspots.

Biology of Coital Behavior: Looking Through the Lens of Mathematical Genomics

The paper investigates receptor sequences across vertebrate species to understand their relationship with mating behavior, finding that genetic and epigenetic factors influence behavioral patterns beyond direct genomic translation.

SARS-CoV-2 variants show a gradual declining pathogenicity and pro-inflammatory cytokine spur, an increasing antigenic and anti-inflammatory cytokine induction, and rising structural protein instability

The paper analyzes SARS-CoV-2 variants to show decreasing pathogenicity and pro-inflammatory cytokines, increasing antigenicity and anti-inflammatory cytokines, and rising structural protein instability across variants.

An Issue of Concern: Unique Truncated ORF8 Protein Variants of SARS-CoV-2

The paper identifies 47 unique truncated ORF8 protein variants in B.1.1.7 SARS-CoV-2 sequences and defines nine possible variants based on physicochemical properties.

Implications Derived from S-Protein Variants of SARS-CoV-2 from Six Continents

The paper analyzes S-protein variants of SARS-CoV-2 from six continents, finding North America has the most unique variants, which may spread globally, suggesting travel restrictions and vaccine updates are needed.

Notable sequence homology of the ORF10 protein introspects the architecture of SARS-COV-2

The paper analyzes sequence variations and structural properties of SARS-CoV-2 ORF10 protein to assess its role in viral pathogenicity and potential as a pharmaceutical target.

A unique view of SARS-CoV-2 through the lens of ORF8 protein

This study analyzes the ORF8 protein of SARS-CoV-2 and its mutations across human, bat, and pangolin hosts to understand its role in immune evasion and evolutionary dynamics.

Possible transmission flow of SARS-CoV-2 based on ACE2 features

The paper analyzes ACE2 receptors across nineteen species to propose a possible SARS-CoV-2 transmission flow based on receptor-binding domain interactions.

Variability of Accessory Proteins Rules the SARS-CoV-2 Pathogenicity

The paper analyzes variations in SARS-CoV-2 accessory proteins across global proteomes and finds ORF3a has the highest unique variations, suggesting these variations may influence pathogenicity.