Author

Jason Lequyer

Mount Sinai HospitalORCID 0000-0002-9580-9640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Evgueni A. IvakineiD· 1 shared Joyce YaniD· 1 shared Laurence PelletieriD· 1 shared Liangchi Zhou· 1 shared Nitya GulatiiD· 1 shared Reid A. Brewer· 1 shared Ronald D. CohniD· 1 shared Steven Erwood· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Evgueni A. IvakineORCID

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1 paper

Recent·Most cited

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, Joyce Yan, Nitya Gulati, Reid A. Brewer, Liangchi Zhou, Laurence Pelletier, Evgueni A. Ivakine, Ronald D. Cohn

The paper uses CRISPR prime editing to functionally interpret variants in NPC1 and BRCA2 genes by haploidizing cell lines and scoring 256 and 465 variants respectively.

Nature Biotechnology · Feb 21, 2022Peer-reviewedGenetics