Laurence Pelletier

The paper shows M1 macrophages transfer mitochondria to myocytes via tunneling nanotubes, enhancing ATP production and progesterone withdrawal, which initiates labor.

The paper introduces VIVOS, a 3D human vascular platform that links intraluminal flow to endothelial state transitions and vessel remodeling through YAP/TAZ-Apelin signaling.

The paper introduces a CRISPR-based system called qTAG to improve the efficiency and flexibility of endogenous protein tagging through optimized repair cassettes.

The paper uses CRISPR prime editing to functionally interpret variants in NPC1 and BRCA2 genes by haploidizing cell lines and scoring 256 and 465 variants respectively.