Madeline M Keenen

Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

This study compares syncytiotrophoblast gene expression in placental tissue and trophoblast organoids using snRNA-seq, identifying distinct nuclear subtypes and environmental influences on STB gene expression.

Phase separation and nucleosome compaction are governed by the same domain of Polycomb Repressive Complex 1

This study shows that a domain in CBX2 is required for both phase separation of PRC1 and nucleosome compaction, linking these processes to developmental patterning.