An automated high-content synaptic phenotyping platform in human neurons and astrocytes reveals a role for BET proteins in synapse assembly
Martin H. Berryer, Gizem Rizki, Anna J. Nathanson, Jenny A. Klein, Darina Trendafilova, Sara G. Susco, Daisy Lam, Angelica Messana, Kristina M. Holton, Kyle W. Karhohs, Beth A. Cimini, Kathleen Lindahl Pfaff, Anne Elizabeth Carpenter, Lee L. Rubin, Lindy E. Barrett
The paper develops an automated high-content synaptic phenotyping platform in human neurons and astrocytes, identifying BET inhibitors as key regulators of synapse assembly.
eLife · Apr 12, 2023Peer-reviewedNeuroscience