Cell BiologyCell ReportsPeer-reviewed
ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability
Hana Maldivita Tambrin, Yun Liu, Kexin Zhu…·Alexander Ludwig
This study identifies ARHGAP12 as a regulator of the paracellular leak pathway by suppressing F-actin assembly at tight junctions without affecting ion flux.