Author

Jaclyn N. Highland

University of Maryland, BaltimoreORCID 0000-0002-9600-2830Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacqueline Lovett· 2 shared Panos ZanosiD· 2 shared Ruin MoaddeliD· 2 shared Todd D. GouldiD· 2 shared Alain Michel GardieriD· 1 shared Brent W. StewartiD· 1 shared Carleigh E. Jenne· 1 shared Carlos A. ZarateiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Jacqueline Lovett

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2 papers

Recent·Most cited

NeuroscienceNeuropharmacologyPeer-reviewedJul 14, 2024

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.

Thi Mai Loan Nguyen, Jean‐Philippe Guilloux, Céline Defaix…·Alain Michel Gardier

The paper investigates how ketamine's metabolism via hepatic CYP450 enzymes affects its antidepressant effects, finding that (6)-HNKs mediate sustained antidepressant actions.

3 citations

mousestatistical model

NeuroscienceNature NeurosciencePeer-reviewedAug 30, 2022

Experimenter sex modulates mouse biobehavioural and pharmacological responses

Polymnia Georgiou, Panos Zanos, Ta-Chung M. Mou…·Todd D. Gould

This study shows that the sex of human experimenters affects mouse behaviors, stress responses, and drug responses like ketamine, mediated by CRF neurons.

135 citationstop 1%

mouseexperimental assay