Author

Jacqueline Lovett

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Jaclyn N. HighlandiD· 2 shared Panos ZanosiD· 2 shared Ruin MoaddeliD· 2 shared Todd D. GouldiD· 2 shared Alain Michel GardieriD· 1 shared Brent W. StewartiD· 1 shared Carleigh E. Jenne· 1 shared Carlos A. ZarateiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Jaclyn N. HighlandORCID

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2 papers

Recent·Most cited

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.

Thi Mai Loan Nguyen, Jean‐Philippe Guilloux, Céline Defaix, Indira Mendez‐David, Isabelle Etting, Jean‐Claude Alvarez, Josephine Cecelia McGowan, Jaclyn N. Highland, Panos Zanos, Jacqueline Lovett, Ruin Moaddel, Emmanuelle Corruble, Denis Joseph Paul David, Todd D. Gould, Christine Ann Denny, Alain Michel Gardier

The paper investigates how ketamine's metabolism via hepatic CYP450 enzymes affects its antidepressant effects, finding that (6)-HNKs mediate sustained antidepressant actions.

Neuropharmacology · Jul 14, 2024Peer-reviewedNeuroscience

Experimenter sex modulates mouse biobehavioural and pharmacological responses

Polymnia Georgiou, Panos Zanos, Ta-Chung M. Mou, Xiaoxian An, Danielle M. Gerhard, Dilyan I. Dryanovski, Liam E. Potter, Jaclyn N. Highland, Carleigh E. Jenne, Brent W. Stewart, Katherine J. Pultorak, Peixiong Yuan, Chris F. Powels, Jacqueline Lovett, Edna F. R. Pereira, , Todd D. Gould

This study shows that the sex of human experimenters affects mouse behaviors, stress responses, and drug responses like ketamine, mediated by CRF neurons.

Nature Neuroscience · Aug 30, 2022Peer-reviewedNeuroscience