Author

Natasja G. Lieuwes

Maastricht UniversityORCID 0000-0002-9606-0889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ala YarominaiD· 1 shared Alexander Marie-Madeleine Adrianus van der WieliD· 1 shared Èlia Prades-SagarraiD· 1 shared Jan TheysiD· 1 shared Jennifer JungiD· 1 shared Jeremy S. SettoniD· 1 shared Kim Rosalie KampeniD· 1 shared Lesley SchuitmakeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ala YarominaORCID

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1 paper

Recent·Most cited

Deficiencies in the Fanconi Anemia or the Homologous Recombination Pathway enhance the antitumor effects of the novel hypoxia-activated prodrug CP-506

Lesley Schuitmaker, Alexander Marie-Madeleine Adrianus van der Wiel, Natasja G. Lieuwes, Rianne Biemans, Nikki A.M. Mutsters, Jennifer Jung, Victoria Claudino Bastos, Èlia Prades-Sagarra, Sheng Kuang, Jeremy S. Setton, Sabine A. S. Langie, Kim Rosalie Kampen, Jan Theys, Ala Yaromina, Ludwig Jerome Dubois, Philippe Lambin

This study shows that deficiencies in Fanconi Anemia or homologous recombination pathways enhance the antitumor effects of CP-506, a hypoxia-activated prodrug, through synthetic lethality mechanisms.

Molecular Therapy Oncology · Feb 24, 2026Peer-reviewedCancer Biology