Author

Jan Theys

Maastricht UniversityORCID 0000-0002-9718-8251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ala YarominaiD· 1 shared Alexander Marie-Madeleine Adrianus van der WieliD· 1 shared Èlia Prades-SagarraiD· 1 shared Jennifer JungiD· 1 shared Jeremy S. SettoniD· 1 shared Kim Rosalie KampeniD· 1 shared Lesley SchuitmakeriD· 1 shared Ludwig Jerome DuboisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ala YarominaORCID

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1 paper

Recent·Most cited

Cancer BiologyMolecular Therapy OncologyPeer-reviewedFeb 24, 2026

Deficiencies in the Fanconi Anemia or the Homologous Recombination Pathway enhance the antitumor effects of the novel hypoxia-activated prodrug CP-506

Lesley Schuitmaker, Alexander Marie-Madeleine Adrianus van der Wiel, Natasja G. Lieuwes…·Philippe Lambin

This study shows that deficiencies in Fanconi Anemia or homologous recombination pathways enhance the antitumor effects of CP-506, a hypoxia-activated prodrug, through synthetic lethality mechanisms.

1 citation

humanexperimental assay

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