Author

Ludwig Jerome Dubois

Maastricht UniversityORCID 0000-0002-8887-4137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ala YarominaiD· 1 shared Alberto BardelliiD· 1 shared Alexander Marie-Madeleine Adrianus van der WieliD· 1 shared Carmen López‐IglesiasiD· 1 shared Èlia Prades-SagarraiD· 1 shared Erik A.L. BiesseniD· 1 shared Erwin Wijnands· 1 shared Frank VerhaegeniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Ala YarominaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Deficiencies in the Fanconi Anemia or the Homologous Recombination Pathway enhance the antitumor effects of the novel hypoxia-activated prodrug CP-506

Lesley Schuitmaker, Alexander Marie-Madeleine Adrianus van der Wiel, Natasja G. Lieuwes, Rianne Biemans, Nikki A.M. Mutsters, Jennifer Jung, Victoria Claudino Bastos, Èlia Prades-Sagarra, Sheng Kuang, Jeremy S. Setton, Sabine A. S. Langie, Kim Rosalie Kampen, Jan Theys, Ala Yaromina, Ludwig Jerome Dubois, Philippe Lambin

This study shows that deficiencies in Fanconi Anemia or homologous recombination pathways enhance the antitumor effects of CP-506, a hypoxia-activated prodrug, through synthetic lethality mechanisms.

Molecular Therapy Oncology · Feb 24, 2026Peer-reviewedCancer Biology

Adrenergic signaling induces a pro-tumorigenic B cell state in colorectal cancer

Meike S. Thijssen, Simone L. Schonkeren, Linde Coolkens, Yuchi Zou, Lieve Temmerman, Joëlle de Vaan, Musa Idris, Jorunn Vranken, Kim Wouters, Nathalie Vaes, Marion J. Gijbels, Sharon Scardellato, Erwin Wijnands, Willine J. van de Wetering, Frank Verhaegen, , Veerle Melotte

This study shows adrenergic signaling promotes a pro-tumorigenic B cell state in colorectal cancer by altering their transcriptome and function, linking neuronal activity to immune responses and patient survival.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology