Author

Natasha L. Pacheco

National Institutes of HealthORCID 0000-0002-9617-8887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aldi T. Kraja· 2 shared Amy R. BentleyiD· 2 shared Anh N. DoiD· 2 shared Ayush GiriiD· 2 shared Botong Shen· 2 shared C. Charles GuiD· 2 shared Carrie A Karvonen-GutierreziD· 2 shared Christophe M. LefèvreiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Aldi T. Kraja

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicineMolecular PsychiatryPeer-reviewedApr 4, 2025

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations

Pavithra Nagarajan, Thomas W. Winkler, Amy R. Bentley…·Stephen S. Rich

This study identifies 22 novel gene-sleep duration interaction loci for blood pressure traits across 811,405 individuals, highlighting distinct genetic influences of short and long sleep on cardiovascular health.

2 citations

humanGWAS summary statistics

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Genetic & Genomic MedicinemedRxivPreprintSep 2, 2024

A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances

Raymond Noordam, Wenyi Wang, Pavithra Nagarajan…·Rima Destya Triatin

This study identifies 17 genetic loci associated with sleep duration and lipid levels, offering potential druggable targets for dyslipidemia in individuals with sleep disturbances.

1 citation

humanGWAS summary statistics

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NeuroscienceeLifePeer-reviewedAug 21, 2019

BDNF/TrkB.T1 signaling is a novel mechanism for astrocyte morphological maturation

Leanne Melissa Holt, Raymundo D. Hernandez, Natasha L. Pacheco…·Michelle Lynne Olsen

This study identifies BDNF/TrkB.T1 signaling as critical for astrocyte morphological maturation, showing increased complexity and synaptogenesis in its presence.

173 citationstop 1%

mouseexperimental assay

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