Author

Nadia A. Ameen

Yale UniversityORCID 0000-0002-9619-4932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:rat· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Kaelyn SumigrayiD· 3 shared Anderson Kenedy SantosiD· 2 shared Eleanor Zagoren· 2 shared Jason Gang Jin· 2 shared Alexandra McCarroniD· 1 shared Caroline MuileriD· 1 shared David Gonzalez· 1 shared David ParsonsiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Kaelyn SumigrayORCID

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3 papers

Recent·Most cited

A second wave of Notch signaling diversifies the intestinal secretory lineage

Eleanor Zagoren, Nicolas Dias, Anderson Kenedy Santos, Zachary D. Smith, Nadia A. Ameen, Kaelyn Sumigray

The paper identifies a rare secretory cell type in the intestine, CHEs, and shows that a second wave of Notch signaling is required for their specification.

Development · May 15, 2025Peer-reviewedCell Biology

CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease

Diego Carlos dos Reis, Jason Gang Jin, Anderson Kenedy Santos, Parinaz K. Dastoor, Caroline Muiler, Eleanor Zagoren, Martin Donnelley, David Parsons, Patricia Cmielewski, Nicole Reyne, Alexandra McCarron, Zachary Smith, Kaelyn Sumigray, Nadia A. Ameen

The paper identifies CFTR High Expresser cells in rat small intestine as pH-sensing neuropod cells and links them to CF disease pathogenesis.

Physiology · May 1, 2025Peer-reviewedPhysiology

Fibroblast contractility drives network reorganization and epithelial proliferation in intestinal polyposis

Meilan Li, Yuying Wang, Maria Figetakis, David Gonzalez, Jason Gang Jin, Elizabeth S. McDonald, Nadia A. Ameen, Kaelyn Sumigray

bioRxiv · Jan 8, 2025 · PreprintCell Biology