Author

Zachary Smith

Beaumont Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:E. coli· 1

Frequent Co-Authors

Alexandra McCarroniD· 1 shared Ali YılmaziD· 1 shared Alus M. XiaoliiD· 1 shared Anderson Kenedy SantosiD· 1 shared Andrei SeluanoviD· 1 shared Caroline MuileriD· 1 shared Curtis Wood· 1 shared David ParsonsiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperPhysiology

Alexandra McCarronORCID

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Author profile →

4 papers

Recent·Most cited

Distinct Metabolic Signatures Linked to High-Resolution Computed Tomography Radiographic Phenotypes in Stable and Progressive Fibrotic Lung Disease

GIRISH BALACHANDRAN NAIR, Faizan Faizee, Zachary Smith, Sayf Al‐Katib, Nadia Ashrafi, Ali Yılmaz, Romana Ashrafi Mimi, Sarayu Bhogoju, Vilija Lomeikaite, Juozas Gordevičius, Edward Castillo, Stewart Francis Graham

This study identifies distinct metabolic signatures in stable and progressive IPF/ILD by integrating HRCT scores with metabolomic profiling.

Metabolites · Jan 19, 2026Peer-reviewedCell Biology

Horizontal Gene Transfer of E. coli by direct DNA uptake from extracellular liquid phase

Curtis Wood, Zachary Smith, Lauren Johnson, James W. Lee

The paper evaluates horizontal gene transfer (HGT) in E. coli strains by direct DNA uptake from extracellular liquid phase, finding HGT occurs in DH5 and DH10B but not in K12.

bioRxiv · Nov 21, 2025 · PreprintMolecular Biology

CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease

Diego Carlos dos Reis, Jason Gang Jin, Anderson Kenedy Santos, Parinaz K. Dastoor, Caroline Muiler, Eleanor Zagoren, Martin Donnelley, David Parsons, Patricia Cmielewski, Nicole Reyne, Alexandra McCarron, Zachary Smith, Kaelyn Sumigray, Nadia A. Ameen

The paper identifies CFTR High Expresser cells in rat small intestine as pH-sensing neuropod cells and links them to CF disease pathogenesis.

Physiology · May 1, 2025Peer-reviewedPhysiology

The genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistance

Quanwei Zhang, Gregory Tombline, Julia Ablaeva, Lei Zhang, Xuming Zhou, Zachary Smith, Alus M. Xiaoli, Zhen Wang, Jhih-Rong Lin, Mohammad Reza Jabalameli, Joydeep Mitra, Nha Nguyen, Jan Vijg, Andrei Seluanov, Vadim N. Gladyshev, , Zhengdong D. Zhang

This study identifies genes contributing to beaver longevity and cancer resistance through genomic analysis of gene copy number, expression, and evolutionary changes.

bioRxiv · Jun 25, 2020 · PreprintGenomics