Author

Eleanor Zagoren

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:rat· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Kaelyn SumigrayiD· 3 shared Anderson Kenedy SantosiD· 2 shared Nadia A. AmeeniD· 2 shared Alexandra McCarroniD· 1 shared Carla Becerra Sabrera· 1 shared Caroline MuileriD· 1 shared David ParsonsiD· 1 shared Denis Ostapenko· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Kaelyn SumigrayORCID

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3 papers

Recent·Most cited

ATR promotes genome instability via CENP-A eviction from centromeres under replication stress

Denis Ostapenko, Hang Li, Isabelle Trier, Ross Shamby, Eleanor Zagoren, Carla Becerra Sabrera, Kaelyn Sumigray, Lilian Kabeche

This study shows that ATR promotes genome instability by causing CENP-A eviction from centromeres under replication stress, leading to acentric chromosomes and segregation defects.

bioRxiv · Oct 20, 2025 · PreprintCell Biology

A second wave of Notch signaling diversifies the intestinal secretory lineage

Eleanor Zagoren, Nicolas Dias, Anderson Kenedy Santos, Zachary D. Smith, Nadia A. Ameen, Kaelyn Sumigray

The paper identifies a rare secretory cell type in the intestine, CHEs, and shows that a second wave of Notch signaling is required for their specification.

Development · May 15, 2025Peer-reviewedCell Biology

CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease

Diego Carlos dos Reis, Jason Gang Jin, Anderson Kenedy Santos, Parinaz K. Dastoor, Caroline Muiler, Eleanor Zagoren, Martin Donnelley, David Parsons, Patricia Cmielewski, Nicole Reyne, Alexandra McCarron, Zachary Smith, Kaelyn Sumigray, Nadia A. Ameen

The paper identifies CFTR High Expresser cells in rat small intestine as pH-sensing neuropod cells and links them to CF disease pathogenesis.

Physiology · May 1, 2025Peer-reviewedPhysiology