Nicole Reyne

A longitudinal evaluation of localised chronic Pseudomonas aeruginosa infection in cystic fibrosis rat models

This study evaluates a localized chronic Pseudomonas aeruginosa infection in cystic fibrosis rat models using agar bead delivery, showing no mortality and persistent infection over 9 weeks.

Evaluating an In Vivo Oxidative Stress sensor in cystic fibrosis rat epithelial tissues

The paper evaluates an in vivo oxidative stress sensor in CF rat tissues, finding elevated redox fluctuations in Phe508del rats compared to wildtype.

Mapping Lung Cancer Ventilation Dynamics: A Pilot Mouse Study Using Functional Imaging and Lung Mechanics

This study uses functional imaging and lung mechanics to assess how tumor growth affects lung function in mice, finding significant changes in ventilation and mechanics post-tumor induction.

CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease

The paper identifies CFTR High Expresser cells in rat small intestine as pH-sensing neuropod cells and links them to CF disease pathogenesis.

Functional lung imaging identifies peripheral ventilation changes in mice with muco-obstructive lung disease

This study uses X-ray Velocimetry to identify peripheral ventilation changes in a mouse model of muco-obstructive lung disease.