Author

Leonid S. Metelitsa

Baylor College of MedicineORCID 0000-0002-9639-6630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex Chen· 1 shared Amy N. CourtneyiD· 1 shared Ashley Zhang· 1 shared Boning YangiD· 1 shared Daniela CerdaiD· 1 shared Elisa LandoniiD· 1 shared Erica J. Di Pierro· 1 shared G. WinkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alex Chen

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 1, 2026

A network of bZIP transcription factors and inhibitors enforces differentially proliferative and cytotoxic states in T cells

Jeshua Lan Malroy, Rangapriya Sundararajan, Maria V. Stegantseva…·G. Wink

This study identifies bZIP transcription factors and inhibitors that influence T-cell proliferation and cytotoxicity under exhaustion conditions.

DOI 10.64898/2026.10.28.762687

mouseexperimental assay

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ImmunologybioRxivPreprintApr 18, 2025

IL-18 metabolically reprograms CAR-expressing natural killer T cells and enhances their antitumor activity against neuroblastoma

Gabriel A. Barragán, Daniela Cerda, Elisa Landoni…·Leonid S. Metelitsa

This study shows that IL-18 enhances antitumor activity of CAR-NKT cells against neuroblastoma by promoting metabolic reprogramming and reducing exhaustion markers.

DOI 10.1101/2025.04.18.649551

humanproteomics

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