Author

Yannick C. Lee-Yow

Basic Science and Engineering Initiative, Betty Irene Moore Children’s Heart Center, Lucile Packard Children’s Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CAORCID 0000-0002-9642-9121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jesse M. EngreitziD· 2 shared Marlene RabinovitchiD· 2 shared Aiqin Cao· 1 shared Alison L. MarsdeniD· 1 shared Anshul Bharat KundajeiD· 1 shared Arun PadmanabhaniD· 1 shared Axel ViseliD· 1 shared Benjamin D. Franco· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersGenetic & Genomic Medicine

Jesse M. EngreitzORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Interpreting variants associated with congenital heart disease with a regulatory map of the human fetal heart

X. Rosa Ma, Stephanie D. Conley, Maggie S. Chen, Michael Kosicki, Yifan Lu, Danila Bredikhin, Ran Cui, Maya U. Sheth, Wei‐Lin Qiu, Dulguun Amgalan, Sijie Chen, Robin M. Perelli, Neil Slaven, Michael T. Montgomery, Sarah Fan Xia, , J Engreitz

This study creates a gene regulation map of the human fetal heart to interpret genetic variants associated with congenital heart disease and cardiac traits, identifying valvular interstitial cells as key regulators.

medRxiv · Nov 20, 2024 · PreprintGenetic & Genomic Medicine

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

Tsutomu Shinohara, J.-R. A. J. Moonen, Yoon Hong Chun, Yannick C. Lee-Yow, Kenichi Okamura, Jason M. Szafron, Jordan Kaplan, Aiqin Cao, Lingli Wang, Divya Guntur, Shalina Taylor, Sarasa Isobe, Melody Dong, Weiguang Yang, Katherine Guo, , Marlene Rabinovitch

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

bioRxiv · Feb 2, 2024Cell Biology