Microglia inhibition rescues developmental hypofrontality in a mouse model of mental illness
Mattia Chini, Christoph Lindemann, Jastyn A. Pöpplau, Xiaxia Xu, Joachim Ahlbeck, Sebastian H. Bitzenhofer, Christoph Mulert, Ileana L. Hanganu‐Opatz
The paper identifies pyramidal neurons in the prefrontal cortex as key elements causing abnormal circuit function in a mouse model of mental illness and shows that microglia inhibition rescues these deficits.
bioRxiv · Jan 27, 2018 · PreprintNeuroscience