Author

Wilson Castro

Ludwig Cancer ResearchORCID 0000-0002-9649-9883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Carlos Henrique Venturi RonchiiD· 1 shared Catherine Roger· 1 shared Cathrin BriskeniD· 1 shared Dorian V. ZiegleriD· 1 shared George SflomosiD· 1 shared Giulia Paone· 1 shared Héctor Gallart‐AyalaiD· 1 shared Jaime López‐AlcaláiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Carlos Henrique Venturi RonchiORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

CDK4 inactivation balances resistance to apoptosis with heightened metabolic sensitivity in triple negative breast cancer cells

Dorian V. Ziegler, Kanishka Parashar, Lucía C. Leal-Esteban, Jaime López‐Alcalá, Wilson Castro, Nadège Zanou, Laia Martínez-Carreres, Katharina Huber, Xavier Pascal Berney, Marı́a M. Malagón, Catherine Roger, Marie-Agnès Berger, Yves Gouriou, Giulia Paone, Héctor Gallart‐Ayala, , Lluís Fajas

This study shows CDK4 inhibition in TNBC cells reduces apoptosis sensitivity and disrupts mitochondrial calcium signaling through MERCs, contributing to resistance to CDK4/6 inhibitors.

Nature Communications · Jan 9, 2025Peer-reviewedCancer Biology