Hippo/YAP1 Signaling Regulates the Oligodendrocyte-Astrocyte Fate Switch and Ependymal Gene Expression in Adult Spinal Cord Stem Cells
Sandra E. Joppé, Robert Chevreau, Joey Abou-chaaya, Leonor Garcia, Valeria Hansberg-Pastor, Szimonetta Hideg, Chantal Ripoll, Hussein Ghazale, Antoine Nouhaud, Enzo Lalli, Carmen Ruggiero, Lei Zhang, M Chen, Sabine Lugand, Serge Urbach, , Jean‐Philippe Hugnot
This study identifies YAP1's role in regulating oligodendrocyte-astrocyte fate switch and ependymal gene expression in adult spinal cord stem cells through in vitro experiments and multi-omic profiling.
bioRxiv · Oct 1, 2025 · PreprintCell Biology