Author

Jianning He

Qingdao Agricultural UniversityORCID 0000-0002-9657-9752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:CUT&Tag· 1

Frequent Co-Authors

Dailu GuaniD· 2 shared David Evan MacHughiD· 2 shared Emily L. ClarkiD· 2 shared Guiping ZhaoiD· 2 shared Guoqing ZhangiD· 2 shared Hao LiiD· 2 shared Huaijun ZhouiD· 2 shared Jianqi Yang· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Dailu GuanORCID

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3 papers

Recent·Most cited

A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits

Zhu Meng, Shiwen Zhang, Ziyang Zhuang, Jiayi He, Fei Liu, Lingyun Wu, Xiangrong Sun, Jingsheng Lu, Xinyi Li, Hao Yang, Mian Gong, Xiaolong Du, Qiao Mei, Hao Li, Guoqing Zhang, , Zhangyuan Pan

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

bioRxiv · Aug 26, 2026 · PreprintGenetics✦ In-depth digest

A multi-tissue atlas of genetic regulatory effects in sheep

Mian Gong, Ziyang Zhuang, Xiangrong Sun, Yuan Xu, Huan-Huan Zhang, Yanan Wang, Dailu Guan, Ran Li, Xiaoning Lu, Zhonghao Bai, Pingjie Feng, Meiwen Song, Min Tian, Jingsheng Lu, Mingshan Wang, , Lingzhao Fang

The paper presents a multi-tissue sheep atlas identifying regulatory variants and their effects on molecular phenotypes, revealing allelic heterogeneity and evolutionary patterns.

bioRxiv · Nov 3, 2025 · PreprintGenomics

Single-cell RNA sequencing analysis reveals new insights for intersex gonad initiation and early sex differentiation of goats

Xinxin Cao, Yichen Zhang, Xu D, Mengmeng Du, Xiaokun Lin, Lu Leng, Flor M. Pérez-Campo, Lihui Zhang, Mingzhi Sun, Xiaoxiao Gao, Jianning He, Qinan Zhao, Jianguang Wang, Jinshan Zhao, Hegang Li

This study uses scRNA-seq to analyze goat gonad development, identifying key genes and cell types involved in sex differentiation and intersex conditions.

bioRxiv · Dec 31, 2024 · PreprintDevelopmental Biology