Context-dependent roles for autophagy in myeloid cells in tumor progression
Jayoung Choi, Gayoung Park, Steve Seung-Young Lee, Erin Dominici, Lev Becker, Kay F. Macleod, Stephen J. Kron, Seungmin Hwang
This study shows that autophagy in myeloid cells can either promote or suppress tumor growth depending on the tumor context, highlighting the need for targeted autophagy inhibitors in cancer therapy.
bioRxiv · Jul 12, 2024 · PreprintCancer Biology