PefA, an ALG-2-like Ca2+ sensor, regulates ESCRT and autophagy responses to mycobacterial vacuole damage
Sandra Guallar-Garrido, Angélique Perret, Amado Carreras‐Sureda, Céline Michard, Thierry Soldati
This study identifies PefA, a Ca2+ sensor, as a regulator of ESCRT and autophagy responses to mycobacterial vacuole damage, showing its role in maintaining vacuolar integrity and infection outcomes.
bioRxiv · Jan 30, 2026 · PreprintMicrobiology