PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome
Junjie Xu, Simon Erlendsson, Manvendra Singh, Matthew Regier, Iosune Ibiricu, Gregory Scott Day, Amanda L. Piquet, Stacey Lynn Clardy, Cédric Feschotte, John A. G. Briggs, Jason D. Shepherd
This study shows PNMA2 forms virus-like capsids that trigger an autoimmune response, leading to paraneoplastic neurological syndrome.
bioRxiv · Feb 9, 2023 · PreprintNeuroscience