Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation
Eunhye Park, Hsin‐Yi Kao, Hussam Jourdi, Milenna T. van Dijk, Simon Segura-Carrillo, Kayla W. Tunnell, Jeffrey Gutierrez, Emma Jane Claire Wallace, Matthew Regier, Basma Radwan, Edith Lesburguères, Juan Marcos Alarcón, André Antonio Fenton
This study shows that PCP disrupts neural coordination and cognitive control by dysregulating translation through NR2A-containing NMDARs and mGluR1/5 pathways.
Biological Psychiatry Global Open Science · May 31, 2023Peer-reviewedNeuroscience