Author

Ana Raquel Costa

University of Beira InteriorORCID 0000-0002-9673-4337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ana Catarina DuarteiD· 3 shared Cecília R.A. SantosiD· 3 shared Isabel GonçalvesiD· 3 shared Helena MarcelinoiD· 2 shared José Francisco CascalheiraiD· 2 shared Ana Cristina da Silva Moreira JorgeiD· 1 shared Carolina Lucas· 1 shared Catarina L. FerreiraiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Ana Catarina DuarteORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Taste receptors' profiling in glioblastoma

Ana Raquel Costa, Catarina L. Ferreira, Tânia Bessa-Soares, Ana Catarina Duarte, Isabel Gonçalves, J.E. Cavaco, Isidró Ferrer, Tomomi Furihata, Helena Marcelino, José Francisco Cascalheira, Cecília R.A. Santos

This study examines the expression and function of taste receptors in glioblastoma, finding that multiple TAS2Rs and TAS1R subunits are active in tumor cells and may influence cancer microenvironment interactions.

Biochemical Pharmacology · May 7, 2026Peer-reviewedCancer Biology

Glioblastoma cells taste temozolomide via TAS2R43

Ana Raquel Costa, Ana Catarina Duarte, Isabel Gonçalves, Robert Preissner, José Francisco Cascalheira, Helena Marcelino, Cecília R.A. Santos

This study shows that glioblastoma cells use TAS2R43 to detect temozolomide, affecting drug efficacy by modulating MDRs.

International Journal of Molecular Sciences · Apr 3, 2026Peer-reviewedCancer Biology

Sweet taste receptor regulates proliferation and glucose uptake in glioblastoma cells

Ana Raquel Costa, Ana Catarina Duarte, Ana Cristina da Silva Moreira Jorge, Isabel Gonçalves, Carolina Lucas, Inês R. Matos, Cecília R.A. Santos

This study shows that inhibiting the sweet taste receptor reduces glioblastoma cell viability, migration, and glucose uptake, suggesting it as a potential therapeutic target.

bioRxiv · Jun 27, 2025 · PreprintCancer Biology