Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads
Dan Xue, Mingming Xu, Michael D. Madden, Xiaoying Lian, Ethan A. Older, Conor Pulliam, Yvonne Y. Hui, Zhuo Shang, Gourab Gupta, Manikanda Raja Keerthi Raja, Yuzhen Wang, Armando Sardi, Yaoling Long, Hexin Chen, Daping Fan, , Jie Li
This paper discovers a new class of cancer immunogenic chemotherapeutic leads called aspercyclicins through a high-throughput screening platform and structural elucidation techniques.
Journal of the American Chemical Society · Dec 28, 2024Peer-reviewedBiochemistry