Author

Mark A Naven

University of ManchesterORCID 0000-0002-9703-4009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher Andrew SmithiD· 2 shared Paul A. HumphreysiD· 2 shared Susan J. KimberiD· 2 shared Fabrizio E. ManciniiD· 1 shared Mona Dvir‐GinzbergiD· 1 shared Nicola BatesiD· 1 shared Stuart A. CainiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Christopher Andrew SmithORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Developmental BiologyThe FASEB JournalPeer-reviewedApr 13, 2022

SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation

Christopher Andrew Smith, Paul A. Humphreys, Nicola Bates…·Susan J. Kimber

This study shows that SIRT1 activation increases ECM gene expression but reduces GAG retention during hESC chondrogenesis, suggesting a complex role in cartilage development.

17 citations

humanbulk RNA-seq

Developmental BiologybioRxivPreprintMar 24, 2021

Directed differentiation of hPSCs through lateral plate mesoderm for generation of articular cartilage progenitors

Christopher Andrew Smith, Paul A. Humphreys, Mark A Naven…·Susan J. Kimber

This study differentiates human pluripotent stem cells through lateral plate mesoderm to generate articular cartilage progenitors and preosteoblasts in a chemically defined protocol.

3 citations

humanexperimental assay