Author

Fabrizio E. Mancini

University of ManchesterORCID 0000-0002-3502-0517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Paul A. HumphreysiD· 3 shared Susan J. KimberiD· 3 shared Nicola BatesiD· 2 shared Woods Jon SiD· 2 shared Aleksandr MironoviD· 1 shared Anna NicolaouiD· 1 shared Antony D. AdamsoniD· 1 shared Brenda Aguero Burgos· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersDevelopmental Biology

Paul A. HumphreysORCID

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3 papers

Recent·Most cited

Cell BiologyOsteoarthritis and CartilagePeer-reviewedFeb 4, 2026

Human pluripotent stem cell model of multiple epiphyseal dysplasia with MATN3 mutation identifies altered Matrix organisation and upregulation of the cholesterol biosynthesis pathway

Woods Jon S, Nicola Bates, Stuart A. Cain…·Susan J. Kimber

This study uses hPSCs to model MED with MATN3 mutations, revealing altered matrix organisation and upregulated cholesterol biosynthesis pathway.

DOI 10.1016/j.joca.2026.01.633

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Developmental BiologyScientific ReportsPeer-reviewedFeb 1, 2024

Effect of a retinoic acid analogue on BMP-driven pluripotent stem cell chondrogenesis

Fabrizio E. Mancini, Paul A. Humphreys, Woods Jon S…·Susan J. Kimber

This study shows that adding TTNPB and timed BMP2 to hPSC differentiation improves chondrogenesis, upregulating genes related to skeletal and cartilage development.

8 citations

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintMar 24, 2021

Directed differentiation of hPSCs through lateral plate mesoderm for generation of articular cartilage progenitors

Christopher Andrew Smith, Paul A. Humphreys, Mark A Naven…·Susan J. Kimber

This study differentiates human pluripotent stem cells through lateral plate mesoderm to generate articular cartilage progenitors and preosteoblasts in a chemically defined protocol.

3 citations

humanexperimental assay

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