Alan F. Scott

Comparative genomics and phylogenomics of the Mustelinae lineage (Mustelidae, Carnivora)

This study presents the first comprehensive comparative and phylogenomic analysis of the Mustelinae lineage, revealing genome size variation, chromosomal evolution, and demographic responses to climate cycles across ten species.

Differential sensory and immune gene evolution in sea turtles with contrasting demographic and life histories

The paper analyzes genomes of leatherback and green turtles to identify gene family expansions and demographic differences that may influence their ecological adaptations and conservation status.

A chromosome-length assembly of the Hawaiian Monk seal (Neomonarchus schauinslandi) confirms genomic stability in the Pinnipeds and a prolonged history of "genetic purging"

The paper presents a chromosome-length assembly of the Hawaiian monk seal, revealing genomic stability and low variation, with implications for conservation and evolutionary studies.

Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

The paper benchmarks DNA preservation methods for long-read and long-range sequencing across vertebrates, finding that optimal methods vary by taxa, tissue, and application.

A Phased Canis lupus familiaris Labrador Retriever Reference Genome Utilizing High Molecular Weight DNA Extraction Methods and High Resolution Sequencing Technologies

The paper presents a phased Labrador Retriever reference genome using high molecular weight DNA and high resolution sequencing, improving GWAS variant detection and reducing costs.

Chromosomal-level genome assembly of the scimitar-horned oryx: insights into diversity and demography of a species extinct in the wild

The paper presents a chromosomal-level genome assembly for the scimitar-horned oryx and analyzes genetic diversity and demographic history in captive populations.

Inferring Disease Risk Genes from Sequencing Data in Multiplex Pedigrees Through Sharing of Rare Variants

This paper extends the Rare Variant Sharing method to handle partial variant sharing in multiplex pedigrees, showing improved power over existing methods in simulations and real data.

Detection of de novo copy number deletions from targeted sequencing of trios

The paper develops MDTS, a method for detecting de novo copy number deletions in parent-offspring trios from targeted sequencing, achieving higher precision and scalability than existing tools.

Evaluating the clinical validity of gene-disease associations: an evidence-based framework developed by the Clinical Genome Resource

The paper presents a framework to evaluate the clinical validity of gene-disease associations, validated using representative gene-disease pairs.

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

The paper designs a genotyping array (ADPC) for African-specific genetic variation using whole genome sequences from the CAAPA consortium, improving GWAS for African ancestry populations.

Genome-wide association study of asthma in individuals of African ancestry reveals novel asthma susceptibility loci

This study identifies novel asthma susceptibility loci in individuals of African ancestry through genome-wide association analysis and admixture mapping.