A nucleic acid labeling chemistry reveals surface DNA on exosomes
Filip Bošković, Priyanka Gupta, Jian Zhang, Yamuna Krishnan, Jack W. Szostak
The paper introduces RUNA, a reversible labeling chemistry to distinguish surface DNA from intracellular DNA on exosomes, revealing its role in immune cell interaction.
Proceedings of the National Academy of Sciences · Jun 29, 2026Peer-reviewedBiochemistry