Yamuna Krishnan

The paper introduces RUNA, a reversible labeling chemistry to distinguish surface DNA from intracellular DNA on exosomes, revealing its role in immune cell interaction.

The paper discovers pH gradients within organelles, challenging the assumption of uniform pH and prompting new questions about proton diffusion and its effects on organelle function.

This paper identifies a NGF variant that selectively biases TrkA signaling towards neurotrophic functions without triggering pain, revealing mechanisms for therapeutic targeting of the NGF-TrkA pathway.

The paper shows that specific ligands on phagocytosed cargo activate p38 MAPK signaling, enhancing phagosome maturation and lysosomal delivery in macrophages.