Author

Aubree A. Zimmer

The Ohio State UniversityORCID 0000-0002-9741-4159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Eva KowalinskiiD· 1 shared Félix WeisiD· 1 shared Juan D. AlfonzoiD· 1 shared Laura TengoiD· 1 shared Luciano G. DolceiD· 1 shared Mary Anne T. RubioiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Eva KowalinskiORCID

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1 paper

Recent·Most cited

Sequence-independent substrate selection by the eukaryotic wobble base deaminase ADAT2/3 involves multiple protein domains and distortion of the tRNA anticodon loop

Luciano G. Dolce, Aubree A. Zimmer, Laura Tengo, Félix Weis, Mary Anne T. Rubio, Juan D. Alfonzo, Eva Kowalinski

This study presents the first structure of a eukaryotic ADAT2/3 deaminase bound to tRNA, revealing sequence-independent substrate selection and a novel gating mechanism for substrate entry.

Nature Communications · Nov 8, 2022Peer-reviewedMolecular Biology