Author

Wei-Liang Chen

Baylor College of MedicineORCID 0000-0002-9754-4113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1

Frequent Co-Authors

Aimee Allworth· 1 shared Alessandro CattabianiiD· 1 shared Barbara MandrianiiD· 1 shared Baudouin Del Marmol· 1 shared Catherine E. OtteniD· 1 shared Christos KotsalosiD· 1 shared David Li‐KroegeriD· 1 shared Debdeep DuttaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aimee Allworth

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2 papers

Recent·Most cited

Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

Mengqi Ma, Yiming Zheng, Mingxi Deng, Shenzhao Lu, Xueyang Pan, Xi Luo, Michelle Etoundi, David Li‐Kroeger, Kim C. Worley, Lindsay Catherine Burrage, Lauren S. Blieden, Aimee Allworth, Wei-Liang Chen, Giuseppe Merla, Barbara Mandriani, , Hugo Jozef Bellen

The paper reports seven individuals with PLCG1 variants causing hearing, vision, cardiac, and immune issues, and shows these variants have gain-of-function effects in Drosophila models.

eLife · Aug 27, 2025Peer-reviewedGenetic & Genomic Medicine

STEPS 4.0: Fast and memory-efficient molecular simulations of neurons at the nanoscale

Wei-Liang Chen, Tristan Carel, Omar Awile, Nicola Cantarutti, Giacomo Castiglioni, Alessandro Cattabiani, Baudouin Del Marmol, Iain Hepburn, James Gonzalo King, Christos Kotsalos, Pramod Kumbhar, Jules Lallouette, Samuel A. Melchior, Felix Schürmann, Erik De Schutter

STEPS 4.0 improves scalability, performance, and memory efficiency for stochastic reaction-diffusion simulations of neurons.

Frontiers in Neuroinformatics · Oct 26, 2022Peer-reviewedNeuroscience