Author

Barbara Mandriani

Telethon Institute Of Genetics And MedicineORCID 0000-0002-4139-0602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aimee Allworth· 1 shared Catherine E. OtteniD· 1 shared David Li‐KroegeriD· 1 shared Debdeep DuttaiD· 1 shared Diego CarrellaiD· 1 shared Diego di BernardoiD· 1 shared Diego Luis MedinaiD· 1 shared Elizabeth BlueiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Aimee Allworth

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic & Genomic MedicineeLifePeer-reviewedAug 27, 2025

Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

Mengqi Ma, Yiming Zheng, Mingxi Deng…·Hugo Jozef Bellen

The paper reports seven individuals with PLCG1 variants causing hearing, vision, cardiac, and immune issues, and shows these variants have gain-of-function effects in Drosophila models.

2 citations

Drosophilaexperimental assay

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedDec 10, 2017

gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning

Francesco Napolitano, Diego Carrella, Barbara Mandriani…·Diego di Bernardo

gene2drug prioritizes drugs based on their impact on transcriptional pathways of target genes, validated both computationally and experimentally for two drug repositioning cases.

110 citationstop 4%

mousebulk RNA-seq

𝕏 PostBluesky