IL-1 instructs para-bronchial cuff fibroblasts to organize lung antibody secreting cell niches during continued antigen exposure
Inés Lammens, Jozefien Declercq, Andrew Stephen Brown, Ursula Smole, Kim Deswarte, Esther Hoste, Karen Herreman, Chananchida Sang-aram, Robin Browaeys, António P. Baptista, Ruth Seurinck, Yvan Saeys, Philippe Gevaert, Hamida Hammad, Bart N. Lambrecht, Stijn Vanhee
Continued allergen exposure drives lung TLO to generate ASCs that home to IL1-instructed para-bronchial cuffs.
bioRxiv · Jan 10, 2026 · PreprintImmunology