NeurosciencebioRxivPreprint
Development of a novel VHH intrabody targeting the N17 region of huntingtin exon 1 protein that prevents inclusion body formation.
Florence D.M. Wavreil, Wouter Pos, Menno Spits…·Eric A. Reits
This paper develops a VHH intrabody that targets the N17 region of mHTT exon 1, reducing insoluble mHTT species and preventing inclusion body formation.
DOI 10.64898/2026.04.09.716913