Christophe Jung

The paper trains a transformer-based model on synthetic Drosophila promoters to predict promoter activity and shows it achieves high accuracy with sequence alone and improves with biological context.

This study determines cryo-EM structures of human MRN complex bound to DNA and TRF2, revealing how MRN senses DNA ends and separates sensing from nuclease activity.

This study identifies PKA as a key effector of the Moody GPCR in Drosophila BBB formation and maintenance, showing its role in regulating cell growth and junction integrity.

The paper studies how Hunchback binding sites in Drosophila enhancers can both repress and enhance activity, revealing a novel mechanism involving Poly-dA stretches.

The paper analyzes Drosophila core promoter function by testing synthetic promoters with and without hormonal activation to understand how mutations affect gene expression.