Author

Jennifer Bré

University of St AndrewsORCID 0000-0002-9793-6432Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

David James HarrisoniD· 1 shared Mustafa ElshaniiD· 1 shared Oliver J. ReadiD· 1 shared Peter MulleniD· 1 shared Ying ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

David James HarrisonORCID

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1 paper

Recent·Most cited

Cancer BiologyPLoS ONEPeer-reviewedSep 16, 2025

A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death

Oliver J. Read, Jennifer Bré, Ying Zhang…·David James Harrison

NUC-3373, a phosphoramidate-modified FUDR, induces DNA damage and DAMPs release in CRC cells, enhancing lymphocyte-mediated cell death and synergizing with PD-1 inhibitors.

3 citations

humanbulk RNA-seq

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