TOPBP1-Dependent DNA Damage Processing Promotes Centromere Loss in an Inviable Xenopus Hybrid
Cordell J. Clark, Riki Terui, Gheorghe Chistol, Rebecca Heald
The paper shows that TOPBP1-dependent DNA damage processing leads to CENP-A loss and centromere destabilization in inviable Xenopus hybrids.
bioRxiv · Sep 18, 2026 · PreprintCell Biology