Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
Corey D. Holman, Alexander P. Sakers, Ryan P. Calhoun, Lan Cheng, Ethan C. Fein, Christopher L. Jacobs, Linus T.-Y. Tsai, Evan D. Rosen, Patrick Seale
This study shows aging impairs beige adipogenesis and adipocyte metabolic responses to cold, identifies Npr3 as a marker gene, and provides insights into age-related adipose tissue dysfunction.
eLife · May 31, 2023Peer-reviewedDevelopmental Biology