Ryan P. Calhoun

This study shows that SOX4 reprograms adipose stromal cells into CAF-like cells in obesity, promoting metabolic disease through TGFβ and MDK signaling.

This study uses continuous glucose monitoring and indirect calorimetry in mice to assess metabolic responses to various physiological stressors, revealing dynamic changes in glycemia and energy expenditure.

This study investigates how the GKRP P446L variant affects hepatic lipid and cholesterol metabolism by reducing GCK activity and increasing cholesterol synthesis.

This study shows PRDM16 maintains SMC identity and regulates atherosclerotic plaque composition by inhibiting synthetic gene programs during SMC fate switching.

This study identifies IRF2BP2 as a repressor of adipocyte lipolysis, showing its role in regulating lipolysis-related genes and metabolic homeostasis.

This study shows aging impairs beige adipogenesis and adipocyte metabolic responses to cold, identifies Npr3 as a marker gene, and provides insights into age-related adipose tissue dysfunction.