Author

Alexander P. Sakers

Broad InstituteORCID 0000-0003-2010-7211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Corey D. HolmaniD· 2 shared Lan ChengiD· 2 shared Patrick SealeiD· 2 shared Anthony R. Angueira· 1 shared Chihiro Okada· 1 shared Christopher L. JacobsiD· 1 shared Ethan C. FeiniD· 1 shared Evan D. RoseniD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Corey D. HolmanORCID

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2 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedMay 31, 2023

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

Corey D. Holman, Alexander P. Sakers, Ryan P. Calhoun…·Patrick Seale

This study shows aging impairs beige adipogenesis and adipocyte metabolic responses to cold, identifies Npr3 as a marker gene, and provides insights into age-related adipose tissue dysfunction.

41 citationstop 2%

mousebulk RNA-seq

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Developmental BiologyNature MetabolismPeer-reviewedApr 12, 2021

Defining the lineage of thermogenic perivascular adipose tissue

Anthony R. Angueira, Alexander P. Sakers, Corey D. Holman…·Patrick Seale

This study identifies the cellular origins of perivascular adipose tissue using single-cell transcriptomics, fate mapping, and adipogenesis assays, revealing fibroblastic and smooth muscle progenitors.

142 citationstop 1%

mousescRNA-seq

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