Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis
Franziska Peters, Susanne Brodesser, Kai Kruse, Hannes C. A. Drexler, Jiali Hu, Dominika Lukas, Esther von Stebut, Martin Krönke, Carien M. Niessen, Sara A. Wickström
This study identifies CerS4's role in regulating hair follicle stem cell niche formation through sphingolipid metabolism, impacting skin homeostasis and barrier function.
bioRxiv · Jan 9, 2024 · PreprintDevelopmental Biology